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Attenuation of the development of morphine dependence/tolerance by nefiracetam : involvement of adenosine 3' :5'-cyclic monophosphate systemITOH, Akio; SHIOTANI, Tadashi; NAKAYAMA, Shinobu et al.Behavioural brain research. 2000, Vol 115, Num 1, pp 65-74, issn 0166-4328Article

Double-Blind Treatment of Apathy in Patients with Poststroke Depression Using NefiracetamROBINSON, Robert G; JORGE, Ricardo E; CLARENCE-SMITH, Kathleen et al.The Journal of neuropsychiatry and clinical neurosciences. 2009, Vol 21, Num 2, pp 144-151, issn 0895-0172, 8 p.Article

Influence of nefiracetam on NGF-induced neuritogenesis and neural cell adhesion molecule polysialic acid expression : in vivo and in vitro comparisonsODUMERU, O; MURPHY, K. J; O'CONNELL, A. W et al.Behavioural brain research. 1997, Vol 83, Num 1-2, pp 173-178, issn 0166-4328Conference Paper

Investigation of testicular toxicity of nefiracetam, a neurotransmission enhancer, in ratsSHIMADA, Makoto; SHIKANAI, Yukari; SHIMOMURA, Kazuhiro et al.Toxicology letters. 2003, Vol 143, Num 3, pp 307-315, issn 0378-4274, 9 p.Article

Anticonvulsant properties of the novel nootropic agent nefiracetam in seizure models of mice and ratsKITANO, Yutaka; KOMIYAMA, Chika; MAKINO, Mitsuhiro et al.Epilepsia (Copenhagen). 2005, Vol 46, Num 6, pp 811-818, issn 0013-9580, 8 p.Article

Testicular toxicity induced in dogs by nefiracetam, a neutrotransmission enhancerSHIMOMURA, Kazuhiro; SHIMADA, Makoto; HAGIWARA, Miyoko et al.Reproductive toxicology (Elmsford, NY). 2004, Vol 18, Num 3, pp 423-430, issn 0890-6238, 8 p.Article

Double-Blind Randomized Treatment of Poststroke Depression Using NefiracetamROBINSON, Robert G; JORGE, Ricardo E; CLARENCE-SMITH, Kathleen et al.The Journal of neuropsychiatry and clinical neurosciences. 2008, Vol 20, Num 2, pp 178-184, issn 0895-0172, 7 p.Article

Cellular mechanism of action of cognitive enhancers : Effects of nefiracetam on neuronal Ca2+ channelsYOSHII, M; WATABE, S; MURASHIMA, Y. L et al.Alzheimer disease and associated disorders. 2000, Vol 14, pp S95-S102, issn 0893-0341, SUP1Conference Paper

Effects of nefiracetam, a novel pyrrolidone-type nootropic agent, on the amygdala-kindled seizures in ratsKITANO, Yutaka; KOMIYAMA, Chika; MAKINO, Mitsuhiro et al.Epilepsia (Copenhagen). 2005, Vol 46, Num 10, pp 1561-1568, issn 0013-9580, 8 p.Article

Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in ratsKITANO, Yutaka; KOMIYAMA, Chika; MAKINO, Mitsuhiro et al.Brain research. 2005, Vol 1057, Num 1-2, pp 168-176, issn 0006-8993, 9 p.Article

Nefiracetam metabolism by human liver microsomes: role of cytochrome P450 3A4 and cytochrome P450 1A2 in 5-hydroxynefiracetam formationFUJIMAKI, Yuko; ARAI, Nobuko; NAKAZAWA, Tsunenori et al.Journal of pharmacy and pharmacology. 2001, Vol 53, Num 6, pp 795-804, issn 0022-3573Article

Nefiracetam elevates extracellular acetylcholine level in the frontal cortex of rats with cerebral cholinergic dysfunctions : an in vivo microdialysis studySAKURAI, T; KATO, T; MORI, K et al.Neuroscience letters. 1998, Vol 246, Num 2, pp 69-72, issn 0304-3940Article

Effects of nefiracetam on cerebral adenylyl cyclase activity in rats with microsphere embolism-induced memory dysfunctionTAKEO, Satoshi; MIYAKR-TAKAGI, Keiko; KIKUCHI, Kanako et al.Biological & pharmaceutical bulletin. 2003, Vol 26, Num 3, pp 318-322, issn 0918-6158, 5 p.Article

Presynaptic nicotinic acetylcholine receptors as a functional target of Nefiracetam in inducing a long-lasting facilitation of hippocampal neurotransmissionNISHIZAKI, T; MATSUOKA, T; NOMURA, T et al.Alzheimer disease and associated disorders. 2000, Vol 14, pp S82-S94, issn 0893-0341, SUP1Conference Paper

Effects of nefiracetam on amnesia animal models with neuronal dysfunctionsHIRAMATSU, M; SHIOTANI, T; KAMEYAMA, T et al.Behavioural brain research. 1997, Vol 83, Num 1-2, pp 107-115, issn 0166-4328Conference Paper

Nefiracetam ameliorates learning deficits in older rabbits and may act via the hippocampusWOODRUFF-PAK, D. S.Behavioural brain research. 1997, Vol 83, Num 1-2, pp 179-184, issn 0166-4328Conference Paper

Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor ∈1 subunitMATSUMOTO, Shinji; KANNO, Takeshi; NOMURA, Tamotsu et al.Brain research. 2002, Vol 956, Num 1, pp 178-181, issn 0006-8993, 4 p.Article

Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized miceFENG HAN; NAKANO, Tetsuo; YAMAMOTO, Yui et al.Brain research. 2009, Vol 1265, pp 205-214, issn 0006-8993, 10 p.Article

Early pathophysiological features in canine renal papillary necrosis induced by nefiracetamTSUCHIYA, Yoshimi; YABE, Koichi; TAKADA, Sanae et al.Toxicologic pathology. 2005, Vol 33, Num 5, pp 561-569, issn 0192-6233, 9 p.Article

Effect of nefiracetam, a neurotransmission enhancer, on primary uroepithelial cells of the canine urinary bladderGOTO, Koichi; ISHII, Yoshikazu; JINDO, Toshimasa et al.Toxicological sciences (Print). 2003, Vol 72, Num 1, pp 164-170, issn 1096-6080, 7 p.Article

Basic science and epilepsy: Experimental epilepsy surgeryTANAKA, Tatsuya; HASHIZUME, Kiyotaka; SAWAMURA, Atsushi et al.Stereotactic and functional neurosurgery. 2002, Vol 77, Num 1-4, pp 239-244, issn 1011-6125Conference Paper

Antiepileptic effect of nefiracetam on kainic acid-induced limbic seizure in ratsHASHIZUME, K; KUNIMOTO, M; MAEDA, T et al.Epilepsy research. 2000, Vol 39, Num 3, pp 221-228, issn 0920-1211Article

A 'long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetamNISHIZAKI, T; MATSUOKA, T; NOMURA, T et al.Brain research. 1999, Vol 826, Num 2, pp 281-288, issn 0006-8993Article

Cellular mechanisms underlying cognition-enhancing actions of nefiracetam (DM-9384)YOSHII, M; WATABE, S; SAKURAI, T et al.Behavioural brain research. 1997, Vol 83, Num 1-2, pp 185-188, issn 0166-4328Conference Paper

Nefiracetam facilitates hippocampal neurotransmission by a mechanism independent of the piracetam and aniracetam actionNOMURA, T; NISHIZAKI, T.Brain research. 2000, Vol 870, Num 1-2, pp 157-162, issn 0006-8993Article

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